SARRATO

Serratiopeptidase 10 mg

Sarrato (Serratiopeptidase (serrapeptase)) is a proteolytic enzyme that has fibrinolytic, anti-edemic, and anti-inflammatory activity. Serratiopeptidase is derived from bacteria belonging to the genus Serratia. This enzyme is absorbed through the intestines and transported directly into the bloodstream. Serratiopeptidase binds to alpha 2- macroglobulin in the blood in the ratio of 1:1, which helps to mask its antigenicity but retains its enzymatic activity and is slowly transferred to site of inflammation.

Indications

• Haematoma
• Inflammation
• Musculoskeletal disorders
• Oedema
• Osteoarthritis
• Rheumatoid arthritis
• Thrombosis
• Traumatic surgery

Dosage

The recommended dose is 3 times/day.

Contraindications

Hypersensitivity

Precautions

• Caution should be exercised in patients with history of liver or kidney disease
• During pregnancy and breastfeeding.
• In patients with blood coagulation abnormalities, severe hepatic and renal disturbances or under treatment with anti-coagulants
• May occasionally cause gastrointestinal disturbances such as anorexia, gastric discomfort and nausea.
• Administration should be discontinued when hypersensitive symptoms, such as eruption, appear.
• Avoid excess dosage

Side effects

Skin rash, diarrhea, loss of appetite, gastrointestinal disturbance and nosebleed

Drug interaction

• Anticoagulant / Antiplatelet drugs interacts with serratiopeptidase.
• It might decrease blood clotting. Therefore, taking serratiopeptidase along with medications that also slow clotting might increase the chances of bruising and bleeding.
• Some medications that slow blood clotting include aspirin, clopidogrel (Plavix), diclofenac (Voltaren, Cataflam, others), ibuprofen (Advil, Motrin, others), naproxen (Anaprox, Naprosyn, others), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, warfarin (Coumadin), and others.